From the time John J. Macreedy steps off the train in Black Rock, he feels a chill from the local residents. The town is only a speck on the map and few if any strangers ever come to the place. Macreedy himself is tight-lipped about the purpose of his trip and he finds that the hotel refuses him a room, the local garage refuses to rent him a car and the sheriff is a useless drunkard. It's apparent that the locals have something to hide but when he finally tells them that he is there to speak to a Japanese-American farmer named Kamoko, he touches a nerve so sensitive that he will spend the next 24 hours fighting for his life.

The life of comedienne Fanny Brice, from her early days in the Jewish slums of the Lower East Side, to the height of her career with the Ziegfeld Follies, including her marriage to and eventual divorce from Nick Arnstein.